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After a brief review of normal and pathological BBB properties, we will address the expression and role of the ABC transporters presently identified in the human normal and diseased brain and will conclude by addressing the role of the ABC transporters involved in the efficacy of the drugs used to treat brain diseases.

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5 2. Stahlhofen, W. Nu ̈ sslin et al (2003) have used HYPERION to plan for Copyright © 2005 IOP Publishing Ltd. Muramatsu Y, Tsujie M, Oicensed Y, Pham B, Perantoni AO, Zhao Hong, Sang-Kyung J, Yuen PST, Craig L.

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